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Staff - Tanja Deckert-Gaudig - Nanospectroscopy

Address: Friedrich Schiller University Jena
Institute of Physical Chemistry
Nanospectroscopy - Deckert Group
Lessingstraße 10
07743 Jena
Germany

Room: 137

Tel.: 03641 - 948 322
Fax: 03641 - 948 302

E-mail:

Homepage: http://www.ters.uni-jena.de/

Biography:

Tanja Deckert-Gaudig studied chemistry at the University of Würzburg and received her PhD in organic chemistry in the group of Prof. S. Hünig in 1997. After her parental leave she switched to physical chemistry in 2002. Since then she has been working on Raman spectroscopy and scanning probe microscopy in the group of Prof. V. Deckert.

After working at the Leibniz Institute of Analytical Sciences (ISAS) in Dortmund she joined the Leibniz Institute of Photonic Technology (IPHT) in 2009. In 2011 she and her colleagues were awarded with the Thüringer Forschungspreis for their achievements in the field of Nanoscopy.

Deckert-Gaudig’s main focus is the structural and chemical analysis of biopolymers in particular amyloid fibrils using tip-enhanced Raman scattering (TERS). The usage of TERS in this field is a new approach to study the secondary structure and chemical composition of amyloid fibrils on the single particle level. The results provide valuable information to further deepen the insight into the phenomenon of protein fibrillation.

Selected Publications:

  1. C. Helbing, T. Deckert-Gaudig, I. Firkowska-Boden, G. Wei, V. Deckert, K. D. Jandt,
    Protein Handshake on the Nanoscale: How Albumin and Hemoglobin Self-Assemble into Nanohybrid Fibers.
     ACS Nano, 2018, ASAP.
  1. T. Deckert-Gaudig, A. Taguchi, S. Kawata, V. Deckert,
    Tip-enhanced Raman spectroscopy - from early developments to recent advances.
    Chem. Soc. Rev., 2017, 46, 13, 4077.
  1. T. Deckert-Gaudig, V. Pichot, D. Spitzer, V. Deckert,
    High-resolution Raman Spectroscopy for the Nanostructural Characterization of Explosive Nanodiamond Precursors.
    ChemPhysChem, 2017, 18, 2, 175.
  1. T. Deckert-Gaudig, V. Deckert,
    High resolution spectroscopy reveals fibrillation inhibition pathways of insulin.
    Sci. Rep., 2016, 6, 39622.
  1. H. S. Davies, Pr. Singh, Deckert-Gaudig, V. Deckert, K. Rousseau, C. E. Ridley, S. E. Dowd, A. J. Doig, P. D. A. Pudney, D. J. Thornton, E. W. Blanch,
    Secondary Structure and Glycosylation of Mucus Glycoproteins by Raman Spectroscopies.
    Anal. Chem., 2016, 88, 23, 11609.
  1. T. Deckert-Gaudig, D. Kurouski, M. A. B. Hedegaard, Pu. Singh, I. K. Lednev, V. Deckert,
    Spatially resolved spectroscopic differentiation of hydrophilic and hydrophobic domains on individual insulin amyloid fibrils.
    Sci. Rep., 2016, 6, 33575.
  1. J. Ofner, T. Deckert-Gaudig, K. A. Kamilli, A. Held, H. Lohninger, V. Deckert, B. Lendl
    Tip-Enhanced Raman Spectroscopy of Atmospherically Relevant Aerosol Nanoparticles.
    Anal. Chem., 2016, 88, 19, 9766.
  1. C. C. VandenAkker, M. Schleeger, A. L. Bruinen, T. Deckert-Gaudig, K. P. Velikov, R. M. A. Heeren, V. Deckert, M. Bonn, G. H. Koenderink
    Multimodal Spectroscopic Study of Amyloid Fibril Polymorphism.
    J. Phys. Chem. B, 2016, 120, 34, 8809.
  1. X-M. Lin, T. Deckert-Gaudig, Pr. Singh, M. Siegemann, S. Kupfer, Z. Zang, S. Gräfe, V. Deckert,
    Direct Base-to-Base Transitions in ssDNA Revealed by Tip-Enhanced Raman Scattering.
  1. A. Krasnoslobodtsev, J. Smolsky, T. Deckert-Gaudig, Y. Zhang, V. Deckert, Y. Lyubchenko
    Tip-Enhanced Raman Scattering Reveals Heterogeneity of Secondary Structures in Amyloid Fibrils Formed by Peptide CGNNQQNY.
    Biophys. J., 2016, 110, 3, 400a.
  1. D. P. Cowcher, T. Deckert-Gaudig, V. L. Brewster, L. Ashton, V. Deckert, R. Goodacre
    Detection of Protein Glycosylation Using Tip-Enhanced Raman Scattering.
    Anal. Chem., 2016, 88, 4, 2105.